She confirmed that at least 11 bodies were brought to the JPMC morgue. They included seven men and four women.
More than 70 people received treatment at the hospital, she added. Most of the injured have been discharged.
Among the injured were foreigners staying at the hotel, including some Chinese officials.
Additional police surgeon Dr Kaleem Sheikh said four doctors and hotel duty manager are among the dead.
According to Faisal Edhi, the foreigners present inside the hotel could not understand Urdu because of which some of the rescue effort was hampered.
Guests inside the hotel, desperate to escape the blaze, jumped from windows and scrambled down knotted bedsheets and curtains to leave the building.
SSP District South Karachi Saqib Ismail Memon said rescue teams reached the site promptly and broke window panes to rescue those trapped inside the hotel.
The official said the fire broke out in the kitchen and spread from there, carried along by the air conditioning system in the building.
One of the survivors from the hotel fire spoke to the media stating that she thought she wont be able to make it out alive until help came to the rescue.
Chief Fire Officer KPT Saeed Jadoon said the hotel duty manager died while attempting to contain the fire and save others from the blaze.
The official said the rescue work was completed in three and a half hours and 11 floors of the hotel were all searched and cleared.
Pakistan batsmen Sohaib Maqsood, Umar Amin and Hammad Azam were present in the hotel at the time of the tragedy. UBL cricketers were also staying at the hotel and were evacuated from their rooms following the deadly fire.
Bowler Yasin Murtaza jumped from the second floor to the ground and fractured his ankle. Karamat Ali was injured by broken glass, according to sources.
The cricketers are in Karachi for the Quaid-e-Azam Trophy tournament. Following the incident PCB postponed the third day’s play of the ongoing match, as many of the cricketers were too shaken to play.
The cricketers helped in rescue efforts. UBL team manager Nadeem Khan said Sohaib Maqsood and others helped rescue families trapped inside the hotel. The cricketers also helped some Chinese officials trapped inside the building to evacuate.
A Pakistan International Airlines (PIA) spokesperson confirmed 16 of the airline’s cabin crew members were injured in the blaze. Most of these crew members belong to Islamabad and Peshawar.
The injured were treated at the hospital after which some of them were discharged while others are still at hospital, the spokesperson said.
DIG South Azad Khan confirmed most of the deaths occurred due to suffocation, while one person died due to burns. He said investigation will begin once medical evidence is collected and a case will be registered after survivor accounts start coming in.
The official said there were two fire exits in the hotel. He added the authorities are waiting for a report from the fire department which would tell if the fire alarm set off or not.
He added that so far the evidence collected points to accidental fire and it does not look like a terrorist act.
Chief Minister Sindh Murad Ali Shah took notice of the incident and demanded a report on the hotel fire incident from Commissioner Karachi.
Murad Ali Shah meanwhile called an emergency session over the tragedy which will be attended by Chief Secretary Sindh, Home Secretary and other officials.
Additional IG Karachi Mushtaq Mehar said a police team led by SSP has begun investigation into the incident. He said forensic evidence has been collected from the hotel and will be tested in laboratory.
A case will be filed after a report on the matter is released, he said.
